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Unlike some growthhormone secretagogues, Ipamorelin does not significantly raise ghrelin or cortisol, so appetite spikes and jitters are uncommon

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Unlike older growth hormone secretagogues that spike cortisol and prolactin, Ipamorelin triggers GH release through the ghrelin receptor without the hormonal noise

It promotes sodium retention in the kidneys, which pulls water along with it

Developed and approved in Russia for stroke recovery and cognitive decline

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