Cani PD, Bibiloni R, Knauf C et al (2008) Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
& Ratliff, S
were included (3 clinical trials sponsored by #FFCD, 3 cohorts) 48% metastatic, 45% doublet chemo Key findings : Factors predicting severe toxicities after 3 months of chemo : female sex, cognitive impairment in men, low albumin level, doublet chemo, impaired kidney function Factors predicting mortality at 36 months : altered IADL, anemia, increased neutrophil count, metastatic stage, and single agent chemo These results will allow treatment individualization in elderly CRC patients Patients predicted to be at risk of severe toxicities could be offered more intensive monitoring This work was supervised by Pr Thomas Aparicio & Pr Florence Canoui-Poitrine, and funded by #INCa To view or add a comment, sign in AccendoWave - A Pain #Data Company Eli Lilly is calling on European countries to make urgent improvements to their #Alzheimers disease diagnostic testing practices just weeks after nabbing a new approval on the continent for its Alzheimer's therapy Kisunla

Endocrine Reviews, 40 (6), 785-799
The average calorie intake for females was 1,700 kcal/d, which is also higher than the recommended energy needs, showing excess calorie intake regardless of male or female
doi: 10.2337/dc10-1949