Ozempic is arguably the best-known of them all and gained significant media attention and popularity over the last few years
Weekly dosage schedule Starting dose: 0.25 mg weekly for first 4 weeks Titration phase: 0.5 mg weekly for 4 weeks and then, if tolerated, 1 mg weekly for 4 weeks Maintenance dose for long-term weight management: 1.7 mg once weekly for 4 weeks and then, if tolerated, 2.4 mg once weekly (maximum dose) Dosing considerations If you do not tolerate dose escalation, consult with your healthcare provider and consider delaying the dose escalation for at least 4 weeks
As weight drops and metabolic health improves, overall energy increases
The Ozempic segment held the largest share of 51.9% in 2025
If needle aversion is part of why you want an alternative, semaglutide provides options that tirzepatide currently does not match
If your plan covers Saxenda or Victoza but not Mounjaro or Zepbound, the out-of-pocket difference may make liraglutide the more practical choice