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doi: 10.1631/jzus.B1700401 17 AnantharajuPGGowdaPCVimalambikeMGMadhunapantulaSV

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Indeed, the major amount of orally supplemented CoQ 10 is eliminated via feces, with only a fraction of ingested CoQ 10 reaching the blood and ultimately the various tissues and organs (Bentinger et al., 2003)

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However, it is important to note that Phase 2 trials are smaller and designed primarily to establish dosing and safety, not to provide definitive efficacy data