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Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients
Neuro Endocrinol Lett, 2006
Mostafa DK, Nayel OA, Abdulmalek S, Abdelbary AA, Ismail CA
Rutin improves anxiety and reserpine-induced depression in rats
However, in keeping with our data on receptor pharmacology, increasing the dose to 30 nmol kg 1 , tenfold higher than maximal doses from our studies, shows that tirzepatide does have insulinotropic activity in Glp1r -/- mice or in the presence of a GLP-1R antagonist 5 , demonstrating that tirzepatide can engage the GIPR in mouse beta cells at sufficiently high concentrations
