Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: Implications for drug screening
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-B signaling
Understanding GLP-1 drug development: pharmaceutical cheat sheet Investigational drugs: Those not yet approved by regulatory approvals and not available for public use Clinical trials: Human trials to prove the safety and efficacy of an investigational drug (or an existing drug for a new use): often in comparison to its competitors
Despite significant progress in characterizing the oral and gut microbiota, the intricate mechanisms by which the oral-gut axis shapes systemic health remain only partially understood
It acts as an agonist at glucagon-like peptide-1 receptors, glucose-dependent insulinotropic hormone receptors, and glucagon receptors
This yielded 98,998 segmented cells across 13 sections, with a median of 196 transcripts and 33 unique genes per cell