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The melanoma cells have large nuclei, often with prominent nucleoli, and show nuclear pseudoinclusions due to nuclear membrane irregularity

Metabolic Dysfunction in Alzheimer's Disease and Related Neurodegenerative Disorders

Enhanced hepatic fat oxidation and phospholipid turnover

Zubair et al

Additionally, melatonin may help maintain BBB integrity and function by interfering with angiotensin-converting enzyme 2, which acts as a receptor for viral entry

Regulation of ferroptosis can be achieved generally by interfering with iron metabolism and ROS metabolism, and the ferroptosis process can be suppressed by iron chelators, lipophilic antioxidants, lipid peroxidation, and the depletion of polyunsaturated fatty acids and correlates with the accumulation of lipid-peroxidation markers (Stockwell et al., 2017)