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Before the recent trials, the compound had been used in other rare diseases but not in PWS

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Sitagliptin works by inhibiting the DPP-4 enzyme that destroys glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) hormones, allowing both to function more effectively

While the Phase 2 trial did not specifically stratify outcomes by baseline eGFR, GLP-1 receptor agonists as a class have demonstrated renoprotective effects in at-risk populations

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How GHK-Cu Transforms Your Skin, Hair, Lashes, and Brows One of the best things about GHK-Cu is just how versatile it is