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These medications work by affecting appetite, blood sugar, and gastric emptying, which is central to the stomach paralysis allegations in the GLP-1 litigation

Pharmacological induction of 5-alpha reductase deiciency in rats: Separation of testosterone-mediated and 5-alpha-dihydrotestosterone-mediated effects.Endocrinology,1986, 119, 959-966 18

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The table sets an action threshold of below 70 mg/dL for fasting glucose, which it says warrants provider review

Then tirzepatide raised expectations even higher by targeting two pathways at once, yielding results that approached bariatric surgery