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Animal studies show that gadolinium can cause low glutathione levels.[ref] Mercury is another heavy metal that utilizes glutathione in the detoxification pathways.[ref] Arsenic exposure causes increased glutathione usage

Discussion ROS-induced signals regulate B cell activation and early metabolic reprogramming 97,98 , and a flexible redox system controls B cell differentiation 31,99,100

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10.1007/978-3-319-99375-1_45 Handbook of immunosenescence

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These treatments will show more dramatic results in a short period