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[1] UL : A Tolerable Upper Intake Level (UL) is the maximum daily dose unlikely to cause adverse side effects in the general population

Most human promoter DNA contains at least one of the TFIID binding sites: a TATA box sequence upstream of the transcription start site, the initiator element at the transcription start site and the downstream promoter element

If you feel great at 4mg and want to move faster, you can consider a 3-week block at the next dose instead of 4, but never skip a dose level entirely

In those trials, single and multiple doses were described as generally well tolerated, with adverse events that were predominantly mild and self-limiting