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Nature Reviews Drug Discovery, 2022

Both can be powerful tools when used intentionally and in the right context

The post says the primary risk is loss of therapeutic efficacy rather than acute harm

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In contrast, Melanotan 1 mainly affects pigmentation because it works strongly through MC1R, the receptor that controls melanin production

J Med Chem 51(23):74427448 Kwon DH, Patel J, Lewis-shimmel M, Marro C, Vasilenco A (2015) Retention of glutathione-specific acidity and disruption of intracellular glutathione-redox homeostasis are associated with antibacterial activity in Pseudomonas aeruginosa