In this study, we show that isolated mitochondria exposed to colistin undergo rapid depolarization of the mitochondrial inner membrane, indicating that mitochondrial damage is likely to be an early event in colistin-induced kidney injury
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1 The pathophysiology of glaucoma Glaucoma is a group of chronic, progressive ocular neuropathies characterized by structural changes to the optic nerve rim and retinal nerve fiber layer (RNFL) loss, leading to related visual field defects, and eventual blindness (1, 2)
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A recent clinical study on tuberous sclerosis complex patients with resistance epilepsy revealed that prolonged use of rapamycin for six months reduced seizure frequency by 56.25% (Sadowski et al
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