Simply put, DSIP (delta sleep-inducing peptide) is a naturally occurring neuropeptide linked to sleep regulation and overall recovery
Side effects are usually mild and temporary
And I think there's a lot of industry influence and spit being swapped that can skew decisions and viewpoints, and that's dangerous
The dopamine in this pathway speaks to the subcortical brain areas responsible for initiating movement, therefore a lack of dopamine causes PD patients to have rigidity or akinesia. A popular treatment for PD, L-dopa, is a precursor to dopamine, and helps make up for lost dopamine neurons
Notably, in mice studies, GH secretagogue receptor suppression in adipose tissues protects against obesity and insulin resistance (97), whereas IGF-I increases skeletal muscle insulin sensitivity (98)
doi: 10.1074/jbc.M211558200