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As a result, there were no differences in P 0 and under all treatments, and P max , V cmax and J max were slightly decreased under the HT treatment compared to the NT treatment

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While exposure to long-term therapy is of potential concern, it is uncertain whether drug exposure to GLP-1 receptor agonist therapies for shorter durations is of any clinical consequence 28

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Such studies help clarify how complex biological systems respond to peptide-based interventions under controlled experimental conditions