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We, therefore, believe that the observed cytotoxic effect may not be directly mediated by a reduction in H 2 O 2 in this context, but rather the opposite

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Taken together, the discovery made by Wang et al

Oxidative stress has been implicated in a number of diseases which include atherosclerosis, pulmonary fibrosis, cancer, Parkinson's disease, multiple sclerosis, and aging[6]

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Thereby, as L-NAME uniformly affected all control rats, along with the fundoscopic and microscopic findings, the final clue may be the highly expressed freezing behavior in all control rats, which was completely recovered after BPC 157 therapy was given