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This lends support to the belief that substances from the intestine were involved in the postprandial control of insulin secretion, which was referred to accordingly as the incretin effect

Future studies aim to facilitate and improve the diagnosis process of the disease, not only reducing symptoms but also improving thyroid function and allowing the patient to return to a more comfortable lifestyle

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TMAO has also been found to promote plaque formation by stabilizing and adjusting the assembly of the amyloid- (A) peptide (Yang et al., 1999) and fibrillation of tau protein by inducing the secondary structure formation at the C terminus in vitro (Scaramozzino et al., 2006)