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These functions contribute to overall biological efficiency and system balance

Growth hormone stimulates the liver to produce insulin-like growth factor 1 (IGF-1) , which plays a significant role in promoting growth and development, especially in muscle and bone tissues

Secondary Signaling Beyond the pituitary, its binding to receptors in the hypothalamus results in the orexigenic effect (intense hunger signaling) and the suppression of somatostatin , ensuring that the growth hormone pulse is not prematurely inhibited by the bodys "off-switch" hormone

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