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Unlike many therapeutic peptides, Dihexa can cross the blood-brain barrier and promote BDNF signaling , a key process for: These effects have made Dihexa of great interest in treating neurological diseases, age-related cognitive decline, and more recently, brain fog and fatigue

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Since its isolation and characterisation in the early 1990s, it has become one of the most extensively studied peptides in regenerative biology research, with a broad research profile spanning gastrointestinal, musculoskeletal, vascular, and neurological tissue models