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Cancer cells co-opt nociceptive nerves to thrive in nutrient-poor environments and upon nutrient-starvation therapies

Beyond the frontiers of neuronal types

In rare cases, mild skin irritation may occur in individuals with extremely sensitive skin or when using excessively high concentrations

To date, few radiosensitising drugs have been approved for use clinically ( in vitro and ex vivo models of oesophageal adenocarcinoma ( Metformin is a clinically approved drug used for the management of type II diabetes ( This study demonstrates, through real-time live cell metabolic profiling and transcriptomic profiling, that metformin significantly alters energy metabolism in both in vitro and ex vivo models of rectal adenocarcinoma and importantly, radiosensitises radioresistant rectal cancer cells to clinically-relevant doses of X-ray radiation

We found that irrespective of the route of vitamin B12 administration, serum vitamin B12 levels were increased

Nasto, L