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Start your intake How Semaglutide Weekly Dosing Actually Works Semaglutide is a long-acting GLP-1 receptor agonist with a half-life of approximately seven days, meaning the medication remains active in your body for an extended period after each injection

Seyama, Y

Swallow this medication as a whole with water

doi: 10.1038/s41522-025-00663-4 110 OhH

Semaglutide alternatives that are approved by the FDA include Mounjaro, Zepbound, Foundayo, metformin, Victoza, Saxenda, and more

In one of the studies, patients with a mean baseline body mass index (BMI) of 35.3 kg/m and an average HbA1c of 8.3% were randomized to receive varying doses of GLP-3 (ranging from 1 mg to 12 mg) or placebo over a 36-week study period