Natriuresis and Diuresis Studies in people living with T2DM and obesity have shown that GLP-1 RA administration can induce diuresis and natriuresis [110, 111] that likely contribute to the renoprotective effects of GLP-1 RA
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This work was supported by the National Natural Science Foundation of China (81790640, 32070989, 31872766, 31571075, 82070993, and 31571072), the Ministry of Science and Technology of China (2011CB504602 and 2015AA020512), Shanghai Municipal Science and Technology Major Project (2018SHZDZX01), ZJLab, Shanghai Center for Brain Science and Brain-Inspired Technology, and Sanming Project of Medicine in Shenzhen (SZSM202011015)
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Research shows that GLP-1 medications do not directly bind to or metabolize lamotrigine, so there is no chemical interaction at the liver or kidney level