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Although lack of insurance coverage and cost were barriers for about half of respondents interested in taking GLP-1s, another 36 per cent said they would take the medication if the risk of side-effects was lower

Pickart and Margolina's review provides the broader gene expression context for why these effects occur

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Abstract The glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR) are members of the secretin-like class B family of G-protein-coupled receptors (GPCRs) and have opposing physiological roles in insulin release and glucose homeostasis 1

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Animal findings frequently fail to translate directly into human medicine