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When combined, these effects can amplify in ways that create genuine clinical risk

HC B cells (n = 6) were cultured in 20% HC or SLE serum supplemented with LPX-1 for 72 hours, and plasmacytoid dendritic cells (pDC) (n = 3) were cultured for 24 hours, the level of IgG was assessed by ELISA and type I IFNs by flow cytometry individually

However, it is vital to distinguish between what happens in a lab rat and what happens in a human

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363 Furthermore, icariin has been found to inhibit ferroptosis in synovial cells and exert a protective effect through activation of the Xc /GPX4 axis