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[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Paolisso G., Di Maro G., Pizza G., DAmore A., Sgambato S., Tesauro P., Varricchio M., DOnofrio F

Another study in rats on the same HFD plus 0.25 g LA/100 g body weight demonstrated that SIRT1 and SIRT3 enhanced LA's antioxidant defense by deacetylating Foxo3a and PGC1, thereby reducing oxidative damage of mitochondrial DNA, restoring oxidative balance, and resisting oxidative stress

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