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doi:10.1152/japplphysiol.00945.2010 Sikiric P, Blagaic AB, Strbe S, et al

By the time you notice the lumps or hardened tissue, the damage is done

It's important to understand that immediate results are not to be expected after a single dose

A patient at a 0.50 mg maintenance dose draws 50 units per week about 10 weekly doses per vial

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Intramuscular injections are generally inconvenient due to pain and require healthcare professionals for administration, thus increasing the economic burden on patients which ultimately leads to discontinuation of the treatment