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These CNS studies did not specifically examine immune cells, and there are several confounding factors such as medication status, the method of collection, and mood state at the time of collection/death
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326 Hence, loss of GIPR signalling may play a role in the pathogenesis of insulin resistance and the manifestation of obesity
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According to UHC Policy P 1475-1, the requirements include BMI of 30 or greater, or BMI of 27 or greater with at least one comorbidity such as diabetes, hypertension, sleep apnea, or high cholesterol