Discussion In our practice, GLP-1 RA initiation is considered as a potential adjunct therapy in overweight and obese people with type 1 diabetes
The SMR analyses reported inverse associations of the expression of the GLP1R gene with background and severe nonproliferative DR, suggesting that administration of GLP-1 RAs, which proxy an increased expression of the GLP1R gene, might causally decrease the risk of DR
doi:10.3945/jn.115.211888 Suzuki-Sugihara N, Kishimoto Y, Saita E, et al
Hormones generally fall into 3 catigories, peptide hormones, steroid hormones and amine hormones
The Precision Peptide Genetic Test offered by PlexusDx analyzes key genetic variants including GLP1R rs6923761 and MC4R rs17782313, which influence individual susceptibility to GLP-1 side effects like headaches
In general, DPP-4 inhibitors are effective at promoting moderate lowering of A1C and are associated with few adverse events