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Streptococcus was negatively correlated with D-alanine, N-methylnicotinamide, glycoursodeoxycholicacid 3-sulfate, and positively correlated with chenodeoxycholic acid 3-sulfate, taurodeoxycholic acid

One of the most discussed classes of drugs in this category is GLP-1 receptor agonists, particularly Semaglutide, which is marketed under brand names such as Ozempic, Wegovy, and Rybelsus

They act through different pathways in the brain and body, which means the usual cognitive tests may not be sensitive to the kinds of changes these drugs might produce

In a dose- and time-dependent manner, hyperactivation of Nrf2 diminished oxidative stress by ameliorating cell apoptosis and improving the redox state of the cell (Song et al