However, in that study, Se levels increased from 120 to 250 g/L
Its important to remember that medical weight management isnt a speed run
NICE guidance (NG28 for type 2 diabetes, TA875 for semaglutide 2.4 mg, and TA664 for liraglutide 3 mg) recommends regular monitoring of patients on GLP-1 therapy, with particular attention to tolerability and adverse effects
However, here are some general guidelines: For individuals with a B12 deficiency, a common protocol may involve a daily dosage of 1,000 mcg for one week, followed by the same dosage once weekly, and then once per month after addressing the deficiency
The 75 and 150 mg/kg doses are approximately equivalent to 5 and 10 g of hydroxocobalamin (respectively) in humans based on both body weight and the Cmax of hydroxocobalamin (total cobalamins-(III))
doi:10.1038/s41598-024-77218-8 66