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It works through two complementary mechanismsregulating both appetite (GLP-1) and metabolic efficiency (GIP)

Eating more slowly and choosing smaller portions often helps

However, often the body doesnt respond to these methods due to medical conditions, genetics, or stubborn areas of the body such as belly fat

[2] [3] If a dose is missed, it should be administered as soon as possible within 5 days after the missed dose

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It was in the middle of the Reagan era