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The remaining 1022 subjects who were not part of this analysis were 36.8% male, with a mean (SD) age of 79 (7) years, and 65.9% were high school graduates

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In preclinical models of arthritis, CS12192 has been reported to ameliorate the disease severity and bone destruction, along with immunomodulatory effects such as the suppression of CD4 + T cell activation and reduction in pro-inflammatory cytokine production (114)

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