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2016;12:e1005390

Methods TACE Procedure in vivo All experimental procedures involving animals were approved by the Institutional Animal Ethics Committee of Guizhou Medical University and were performed in accordance with the National Institutes of Health Guidelines for the Care and Use of Laboratory Animals

Some experimental models may observe: Temporary recovery-related response variability Changes in tissue-related sensitivity Adaptation-related physiological variability Individual differences in regenerative-response patterns Administration & Handling Considerations Improper storage, reconstitution, or administration techniques may increase the risk of: Administration-site irritation Local inflammation Reduced peptide stability or effectiveness Additional Research Notes Higher-frequency protocols may increase the likelihood of local irritation or sensitivity-related observations

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