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Additionally, Annao tablet has the potential to enhance the transcription level of Bcl-2 mRNA, augment the ratio of Bcl-2/Bax to impede apoptosis, diminish the count and protein expression of caspase-3 positive cells, decrease the number of neuronal apoptosis at the periphery of cerebral infarction, ameliorate the neurological deficit following ischemia, and elevate the count of positive neurons (Zhang Y

This creates a cascade of metabolic dysfunction that makes traditional weight management approaches less effective during perimenopause.[2] GLP-1 Receptor Agonists: Mechanisms of Action in Perimenopause GLP-1 receptor agonists work through multiple pathways that are particularly relevant to perimenopausal women: Appetite Regulation and Satiety These medications reduce appetite and food cravings by activating satiety centers in the brain and slowing gastric emptying

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Metabolic and glucose regulation : Berberine has been studied for its effects on blood glucose control, with some research suggesting it may improve insulin sensitivity and reduce fasting blood glucose levels through AMPK activation

[DOI] [PubMed] [Google Scholar] 66.Makino H., Tanaka A., Asakura K., et al

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