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The effect intensifies during dose escalation, when patients move from lower to higher amounts of medication over several weeks

Oral tolerance was first observed when guinea pigs given hens egg protein orally were found to become resistant to the anaphylactic reactions normally induced by the ingested protein

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Dual-action GLP-1/GIP receptor agonists like Zepbound can also mimic the action of GIP, a hormone that helps regulate blood sugar levels and metabolism

PCAC will weigh each separately

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