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Schiellerup SP, Skov-Jeppesen K, Windelv JA, Svane MS, Holst JJ, Hartmann B, et al

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doi: 10.2176/nmc.49.546 42 BeresfordHR

Initial glucose-lowering effects typically occur within days to weeks, but maximum benefits including HbA1c reduction and cardiovascular effects may take up to 3 months to fully manifest

Notable examples of these secreted proteins include human chorionic gonadotropin, human placental lactogen (hPL), human GH variant or placental growth hormone, leptin, corticotropin-releasing hormone, placental growth factor (PlGF) all of which are secreted by the placenta into the mothers bloodstream (178, 257265)

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