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NONMEM user's guides

They define PCOS as the presence of two out of three criteria: hyperandrogenism (elevated levels of male hormones, assessed clinically -presence of acne, hirsutism- or biochemically), ovulatory dysfunction (oligo/anovulation, infrequent or absent ovulation), and/or polycystic ovarian morphology on ultrasound: either the presence of 20 or more follicles on a single ovary or ovarian volume above 10 cm3

Ye et al., 2002)

Here are five of the most common reasons : 1

Upon the addition of 0.16% APTES to the solution we observed a distinct increase in the size and size distribution of the solution in Fig

Waste Manag 172:5159