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both BLISS-LN and AURORA 1 trials, essential and recent studies on the use of belimumab and voclosporin on patients with LN, show that not all patients had RAAS blockade prior to randomization (66% of patients on the belimumab arm in BLISS-LN) ( Additionally, we must remember that diuretics can be an essential tool to mitigate proteinuria, especially if combined with RAAS blockade

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Studies also indicate that it plays a vital role in cellular metabolism, DNA repair, and brain function

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