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Thyroid cancer or family history of medullary thyroid carcinoma: Avoid due to regulatory warnings associated with GLP-1 and GLP-1/GIP receptor agonists

Some advanced formulations of weight loss injections activate not just one, but multiple hormonal pathways involved in hunger, blood sugar control, and metabolism

The abdomen is generally the most accessible site for self-injection

The dual action mechanism: GLP-1 and GIP Research suggests that GLP-1 receptor agonism is the primary driver of the slowed gastric emptying that contributes to many gastrointestinal side effects

TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

Effects on Platelets Preclinical Studies Most of the DPP4i have been suggested to have anti-thrombotic effects