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Mitochondrial and synaptic abnormalities in ASD-related syndromes The growing body of evidence reveals that the ability of mitochondria to adapt to the changing environment and energy demand is impaired in various ASD-related syndromes [325, 326]

106,107 Based on the purpose of improving the efficacy of ASNase in hematological malignancies, expanding the use of ASNase and reducing side effects, a new generation of ASNase is being developed (Tables 1, 2)

PMID: 29395054

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