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High levels of DHT, inhibit Wnt5a and -catenin in DPCs, triggering apoptosis via cyclin and c-Myc downregulation [33]

Mitochondria are cholesterol-poor organelles compared to plasma membrane, and this regulated transport of cholesterol in mitochondria plays physiological role in the synthesis of bile acids in liver and steroidogenic hormones in other tissues

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Fluorescence intensities were measured at excitation/emission wavelengths of 488 nm/525 nm using a Leica TCS SP5 confocal microscope