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IGF-1 levels are also highly influenced by nutritional intake, which might hold greater significance from an evolutionary standpoint, as the primary signaling pathways triggered by IGF-1 in metazoans were originally activated by nutrient availability (34)

Causes of TMAU TMAU is caused by the inability of the person to break down a smelly chemical in the body called Trimethylamine (TMA) into the non-odorous form Trimethylamine oxide (TMAO)

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