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Tumour redox state, hypoxia, and acidosis imaging Tumour microenvironmental characteristics such as hypoxia, altered redox balance, and extracellular acidosis have emerged as central determinants of tumour aggressiveness, metastatic potential, and therapeutic resistance (181, 182)

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Pyruvate has been demonstrated to prevent not only diabetic cataracts but also cataracts caused by selenite and ultraviolet radiation 20,21,22,23

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