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And the people who struggle

Fewer cravings they didn't even know were cravings

Placebo-controlled, randomized trial of the addition of once-weekly glucagon-like peptide-1 receptor agonist dulaglutide to titrated daily insulin glargine in patients with type 2 dia-betes (AWARD-9)

Chronic stress can magnify this slowdown, triggering hormonal changes (like rising cortisol) that interfere with the signals and processes needed to keep peptide levels robust

Healthcare providers should consider this limited evidence base when making treatment decisions and should discuss these limitations with patients

J Clin Psychiatry 85:50515 Samms RJ, Christe ME, Collins KA et al (2021) GIPR agonism mediates weight-independent insulin sensitization by Tirzepatide in obese mice