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Concurrently, this ROS burst activates the NF-B pathway, perpetuating pro-inflammatory cytokine secretion (TNF-, IL-1, IL-6) and establishing a vicious cycle of chronic inflammation
10.1177/0269881112463124 30 ClrierE.LaulinJ.LarcherA.Le MoalM.SimonnetG
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Esto compromete la elasticidad y firmeza de la piel, favoreciendo la formacin de arrugas y la prdida de definicin del valo facial
