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Compelling evidence for SGLT2 inhibitors and GLP-1 receptor agonists as first-line therapy in patients with diabetes at very high/high cardiovascular risk

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43 Indeed, this may explain the potent metabolic effects of tirzepatide when pitted against a GLP-1 agonist alone

Common clinical scenarios where the question arises are for patients who are at increased risk due to family history or genetic risk factors for PDAC, as well as individuals with a history of acute or chronic pancreatitis