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Med Chem Res 28:505514

Direct activation by GLP-1 RAs has been shown widely to increase insulin and decrease glucagon secretion in a glucose-dependent manner, resulting in reduced blood glucose levels combined with low risk of hypoglycaemia

Patients should seek urgent medical assessment for severe, persistent abdominal pain with vomiting or bloating, as distinguishing this from UC-related pain requires clinical evaluation

Eric Topol (28:22): Ah, okay

Recent evidence highlights the direct and indirect anti-inflammatory properties of GLP-1, suggesting a potential additional therapeutic strategy for patients with inflammatory bowel disease (IBD)

Weight loss surgery is not for everyone who is severely overweight.[7] Risks of bariatric surgery can include infection, excessive bleeding, blood clots, breathing issues, leaks in the gastrointestinal system, bowel obstruction, gallstones, hernias, hypoglycemia, malnutrition, ulcers, and, in rare cases, death