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Environ Toxicol Pharmacol 58:1120

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Europe Glucagon-Like Peptide-1 Agonists Industry Leaders Novo Nordisk AstraZeneca Eli lilly and Company Sanofi Pfizer *Disclaimer: Major Players sorted in no particular order Recent Industry Developments April 2023: Eli Lilly and Company and Amphastar Pharmaceuticals, Inc

Clinical Evidence: What the Data Shows Phase 3 Trial Results (Zepbound Studies) The REFRAME and related trials demonstrated: Weight Loss Average: 22.5% body weight reduction at 68 weeks Range: 18-28% depending on population Significantly exceeds tirzepatide (21% at comparable doses) Body Composition Preferential loss of visceral fat (the dangerous kind) Better preservation of lean muscle vs

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Blood sugar drops If blood sugar dips too low, this may indicate hypoglycemia, a condition where the glucose in the blood drops below whats healthy, leading to symptoms like lightheadedness, feeling tired, and confusion