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This is where the concept of bioavailability becomes critical

The resultant opening of voltage-dependent L-type Ca 2+ channels increases the intracellular concentration of Ca 2+ , which also acts as a second messenger, augmenting neurotransmitter release [33]

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Bifidobacteria are early colonisers of the infant gut and produce SCFAs, like acetate and lactate, which cross-feed other gut inhabitants, including butyrate producers, such as Faecalibacterium prausnitzii