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Conclusion and future directions With the growing use of GLP-1 agonist medications (currently estimated at one in eight in the US, and one in five women aged 5064 [62]), the need for a thorough assessment of their side effects is becoming increasingly vital in promoting patient health and well-being

Long-term Unknowns As with other relatively new medications, long term effects are unknown

Unlike most peptides, it targets sleep quality, cellular renewal, and longevity through a mechanism tied to the pineal gland

Pfizer had an oral GLP-1 medication in development called danuglipron, but trials were halted in April after the medication was tied to liver toxicity

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